Sirolimus Delayed-Release Tablets for Cats — HCM
From $48 · 4 in the box · 1 month
For cats diagnosed with hypertrophic cardiomyopathy. The same weekly rapamycin (sirolimus) protocol, positioned around the heart — used under the guidance of your own veterinarian and cardiologist.
Shown in your local list price. You are charged this amount at checkout.
Prescription medicine. Use it only under the guidance of your own veterinarian.
Key facts
| Strengths | 0.4 mg · 1.2 mg · 2.4 mg |
|---|---|
| In the box | 4 · 1 month |
| Price | From $48 per box |
| Shipping | $32 flat per order, tracked — about 3 days to Europe |
| Prescription | Prescription medicine. Use it only under the guidance of your own veterinarian. |
| Indication | Positioned for cats diagnosed with hypertrophic cardiomyopathy (HCM) |
| Evidence | Under clinical investigation in feline HCM — not a licensed treatment |
| Form | Delayed-release, acid-resistant tablet |
| Schedule | Once weekly, with food |
| Alongside | Works with your cardiologist’s care, not instead of it |
| Purity | Lab-tested to a 99.9% standard, every batch |
| Status | Prescription medicine. Use it only under the guidance of your own veterinarian. |
Quick answers
What does it cost?
$48 to $393 per box, depending on strength and supply. Shipping is $32 per order, shown before you pay. There is no subscription: you pay per box.
Which strength is right for my pet?
Strengths follow body weight — 0.4 mg: ≈ 1.3 kg (2.8 lb); 1.2 mg: ≈ 3.8 kg (8.4 lb); 2.4 mg: ≈ 7.7 kg (17 lb). Confirm the strength with your own veterinarian before starting.
Who should not use it?
It is not suitable for animals with diabetes or impaired glucose regulation, an active infection, significant liver disease, a planned surgery, or that are pregnant or nursing. Rapamycin can raise blood fats, so bloodwork before and during use matters. Talk to your veterinarian before starting.
How fast is delivery?
Every parcel ships tracked. Typical delivery once it ships: Europe 2–4 days, Türkiye 1–3 days, Gulf (GCC) 3–6 days, Rest of Asia 4–8 days, North America 4–8 days, Oceania 5–9 days.
Do I need a prescription?
It is a prescription medicine. Use it only under the guidance of your own veterinarian, and only where the law of your country allows it.
Can I return it?
If your box arrives damaged or wrong, we replace or refund it. In the EU and the UK you can withdraw within 14 days of delivery and return an unopened box; a box whose seal has been broken cannot be returned, for health-protection reasons.
What rapamycin therapy actually costs →
For the diagnosis you did not want
Hypertrophic cardiomyopathy is the most common heart disease in cats, and most owners hear the word for the first time in a cardiologist’s room. There is no cure, and until recently there was little to offer beyond monitoring. That is beginning to change.
What the research actually shows
Rapamycin (sirolimus) — an mTOR inhibitor studied for over fifty years — is being investigated in feline HCM because the pathway it acts on is involved in how the heart muscle thickens. A masked, placebo-controlled clinical trial in cats with subclinical HCM found low-dose rapamycin was safe and feasible, with early signals worth pursuing. This is an area of active study, not a settled treatment. The only medicine with any approval for feline HCM is a delayed-release sirolimus with conditional FDA approval in the United States for subclinical HCM; none is fully approved, and nothing here is a promise that rapamycin will change the course of the disease.
Where this fits
- It does not replace your cardiologist. It is used alongside your cat’s existing cardiac care, not instead of it.
- It is for owners who have discussed rapamycin with their vet and want it prescribed and monitored properly by that vet.
- Echocardiography and bloodwork stay with your own veterinary team, who use them to keep dosing and monitoring safe.
How the therapy works
One delayed-release, acid-resistant tablet once a week, with food — the same protocol as our feline longevity therapy, calibrated to your cat’s body weight (0.4 mg, 1.2 mg or 2.4 mg). Flavored oral suspensions are available for cats that refuse tablets.
Guided by your own veterinarian
Rapamycin is a prescription medicine. Use it only under the guidance of your own veterinarian, who knows your cat’s history and cardiac workup and can confirm the dose and monitoring. Cats with certain conditions are not candidates, so check with your vet before starting. Lab-tested to a 99.9% purity standard.
Rapavie and Rapamune are the same molecule, not the same medicine
Rapamune is the human transplant product. People find it when they search sirolimus, and the difference is worth a minute.
| Rapavie | Rapamune (human) | |
|---|---|---|
| Form | Delayed-release, acid-resistant tablet | Immediate-release tablet |
| Dosing | Once weekly, with food | Every day |
| Licensed for | Prescription medicine for cats and dogs, used under a veterinarian’s guidance | Human kidney-transplant patients |
| Splitting | Not needed — you choose the strength for your animal’s weight | Labelled to be swallowed whole — not crushed, chewed or split |
📦 Shipping time & tracking
- Every parcel ships fully tracked — the tracking number is emailed the moment the label is created.
- Flat €30 shipping worldwide, shown up front — no surprise fees at checkout.
- Your box ships once your order is confirmed; the delivery windows below are counted from dispatch.